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June 6, 2007
The following information was taken from a Centers for Disease Control and Prevention (CDC) Health Advisory issued May 25, 2007. Additional Missouri-specific information has been added.
CDC has received reports of 138 cases of culture-confirmed Acanthamoeba keratitis (AK) in 35 states (including Missouri) and Puerto Rico, with complete patient data available for 46 case-patients. Thirty-nine of the 46 case-patients wore soft contact lenses. Preliminary information from patient interviews indicates that, among soft contact lens users who reported the use of any type of solution, 21 (58%) reported having used Advanced Medical Optics (AMO) CompleteR MoisturePlusTM Multi-Purpose Solution in the month prior to symptom onset. Out of the 37 case-patients for whom clinical data was available, 9 (24%) failed medical therapy and required or are expected to undergo corneal transplantation.
People who wear soft contact lenses who use Advanced Medical Optics (AMO) CompleteR MoisturePlusTM Multi-Purpose Solution should:
- Stop using the product immediately and discard all remaining solution, including partially used or unopened bottles. Choose an alternative contact lens solution.
- Discard current lens storage container.
- Discard current pair of soft lenses.
- See a health care provider if experiencing any signs of eye infection: eye pain, eye redness, blurred vision, sensitivity to light, sensation of something in the eye, or excessive tearing.
Clinicians evaluating contact lens users with symptoms of eye pain or redness, tearing, decreased visual acuity, discharge, sensitivity to light, or foreign body sensation should consider AK and refer the patient to an ophthalmologist, if appropriate. Early diagnosis can greatly improve treatment efficacy.
Clinicians or microbiology laboratories should report cases of AK to their local public health agency, or to the Missouri Department of Health and Senior Services (DHSS) at 800/392-0272 (24/7). Acanthamoeba isolates should be submitted to the Missouri State Public Health Laboratory (MSPHL) according to instructions provided by MSPHL (see the form on the next page).
For more information, see CDC's Acanthamoeba Infection website at: http://www.cdc.gov/ncidod/dpd/parasites/acanthamoeba/index.htm.
A Food and Drug Administration (FDA) news release and recall notice can be found at:
Questions should be directed to DHSS's Bureau of Communicable Disease Control and Prevention at 573-751-6113, or 866-628-9891.
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